National Centre For Cell Sciences, Pune

The National Centre for Cell Sciences, Pune (NCCS) was established as a national repository of animal cell culture. It also has the mandate to conduct manpower development programmes in animal tissue culture, to extend infrastructural facilities to researchers and institutions in biochemical sciences, and to conduct state-of-the-art  R&D in allied areas.

Cell Repository : This Facility is providing hundreds of cell cultures and different cell lines to several research institutions in the country. The culture collection has increased to 1127 cultures derived from 25 different species, including hybridomas.

Research : The institute at present is doing basic research in the area of  cryopreservation technology for bone marrow, bio-equivalent skin for transplantaion in burns, nevi and vitiligo cases, development of cell cultures from commercially important invertebrates and vertebrates,  endemic and non-endemic sera for IgG4 antibodies of Setaria digitata antigen, identification of melanoma oncogenes, epithelial- mesenchyumal transition, in vitro studies on molecular and cellular interaction lipopolysaccharide with human intestinal mesenchymal cells, study of haemozoin and the effect of protein alteration on the fetuses whose mother faced a low protein diet throughout gestation.

Major leads towards development of product/process :

• Cryopreservation of bone marrow to enable setting up of stem cell banks
• Cultured fetal hepatocytes for preparation of bio-artificial liver support device in case of acute and chronic liver failure.

The institute continues to create a scientific base and focusses its activities on pursuit of fundamental research and solutions derived for tangible public utility. The centre has made very good progress in basic research in providing services to the scientific community.

For further information, please contact Dr G.C. Mishra, Director, NCCS, NCCS Complex, Ganeshkhind, Pune-411007 E Mail: infonccs@giaspn01.vsnl.net.in

Website address : http://www.nccs.res.in

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